Dr. Pascal Kwangwari
Translational Research

Research in Hepatology & Liver Disease

Dr. Pascal's research focuses on hepatocellular carcinoma (liver cancer) — particularly risk stratification, early detection biomarkers, and therapeutic response prediction in Chinese patient populations. His work bridges clinical hepatology with translational molecular research.

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Lab & Research

Research In Motion

Clinical and surgical research workflow
Dr. Pascal Kwangwari in the surgical suite
Research slide on translational immunology and liver disease
Laboratory research workflow and sample preparation
Dr. Pascal Kwangwari working in the laboratory
Cell culture and laboratory samples in a biosafety cabinet
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Research Focus Areas

Areas of Investigation

Hepatocellular Carcinoma (HCC)

Risk stratification, recurrence prediction, and biomarker identification in HBV-related and NASH-related liver cancer.

Liver Disease Progression

Non-alcoholic fatty liver disease (NAFLD) to cirrhosis transition mechanisms and clinical staging validation.

Therapeutic Response Biomarkers

Identifying molecular markers that predict response to systemic therapy in advanced hepatocellular carcinoma.

China-Africa Health Outcomes

Comparative epidemiology and clinical outcome differences for African patients treated within the Chinese healthcare system.

Publications

Research Publications

Figure from Predictive value of neutrophil-to-lymphocyte ratio in recurrent HCC after repeat hepatectomy or salvage liver transplantation
PublishedHepatology International2025
Predictive value of neutrophil-to-lymphocyte ratio in recurrent HCC after repeat hepatectomy or salvage liver transplantation
Kwangwari P, et al.
doi:10.1007/s12072-025-10786-7
  • ArchitectureBiomarker response model
  • DesignAdvanced HCC therapeutic-response analysis
  • ResultsInflammation-response signal placeholder
Figure from Acute carbon monoxide poisoning with low saturation of carboxyhaemoglobin: a forensic retrospective study in Shanghai, China
PublishedScientific Reports2021
Acute carbon monoxide poisoning with low saturation of carboxyhaemoglobin: a forensic retrospective study in Shanghai, China
Kwangwari P, et al.
doi:10.1038/s41598-021-97436-8
  • ArchitectureRecurrence-risk stratification
  • DesignRepeat hepatectomy vs. salvage liver transplant cohort
  • ResultsNLR as a predictor of post-recurrence outcomes
PublishedScientific Reports2021
Prognostic Value of Preoperative Inflammatory Markers in Predicting Recurrence After Hepatic Resection for HBV-Related Hepatocellular Carcinoma
Kwangwari P, et al.
  • ArchitectureForensic case-series analysis
  • DesignRetrospective autopsy review, Shanghai region
  • ResultsLow-COHb saturation cases re-characterised
Experience

Clinical & Research Experience

Translational R&D Researcher — Hepatobiliary Oncology & Transplant Immunology
Fudan University Zhongshan Hospital
Sep 2023 – Present
Research
Research Associate — Post-Transplant Immunopathology & GVHD
Fudan University Zhongshan Hospital
Aug 2024 – Sep 2025
Research
Clinical Research Associate Intern — CAR-T Cell Therapy
Shanghai Origin Cell Therapeutics
Jul 2021 – Aug 2021
Clinical
Undergraduate Research Analyst — Forensic Epidemiology & Biomarker Study
Fudan University Forensic Science
2021
Research
Technical Skills

Skills & Competencies

In Vivo Models
  • —Murine hepatic ischemia-reperfusion
  • —Intrasplenic tumor injection
  • —Retro-orbital venous sampling
  • —Liver perfusion
  • —Microsurgical dissection
Cell & Molecular
  • —THP-1 macrophage polarization
  • —ELISA
  • —Western blot
  • —PCR
  • —TUNEL apoptosis
  • —CCK-8 viability
  • —Transwell migration / invasion
Genomics & Omics
  • —RNA-sequencing interpretation
  • —Mass spectrometry proteomics
  • —IHC / IF markers
  • —CRISPR/Cas9 (conceptual design)
Data & Analysis
  • —RStudio · GraphPad Prism · SPSS
  • —Biomarker study design
  • —Retrospective cohort analysis
  • —EMR dataset management
  • —GCP compliance
  • —Scientific writing

Interested in Research Collaboration?

Open to joint research, co-authorship, and data-sharing opportunities in hepatology and liver disease.

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